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Optimizing Lab Workflow with LIS Systems and Lab LIMS
June 6, 2025
Testing labs process a heavy workload of samples daily. They rely on established, smooth-running laboratory workflow management and diagnostic lab software tools to manage and process samples and data.
Healthcare organizations streamline clinical lab workflows and enhance data management by leveraging laboratory information systems (LIS software) and laboratory information management systems (lab LIMS).
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What is Lab Information Management System (LIMS) Software?
A comprehensive LIS system or lab LIMS can automate all aspects of a laboratory’s operations, from sample processing and lab instrument integration to data management and reporting.
A LIS system or lab LIMS simplifies the storage and retrieval of test data associated with processed samples, allowing stakeholders to access reports on test results, audit trails, sample quality analysis, and even generated invoices.
The best LIMS lab information management system software improves a lab’s turnaround time by automating clinical lab workflow for sample tracking, processing, and recording test results. The best LIS and lab LIMS leverage advances in data storage approaches (such as cloud storage) and organizational tools to securely store and link large volumes of data to the proper source.
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For example, each specimen in a modern LIS system or lab LIMS receives a lab track system unique ID linked to both the test result and the sample. This sample tracking automation streamlines processes and minimizes tracking and data recording errors.
Advanced LIS systems and LIMS lab management software go beyond basic sample tracking and processing—they also help ensure compliance with regulatory standards (such as Good Laboratory Practice), providing early indicators of adherence to quality assurance (QA) protocols before audits occur.
For high-volume testing laboratories, a validated LIS laboratory information system or lab LIMS serves as the foundation, supporting both operational efficiency and regulatory readiness.
The Use of Medical Laboratory Information System Software in Pathology Labs
A medical laboratory information system software package digitizes a lab’s workflow management. This type of pathology lab software is designed to automate several clinical lab and pathology practice processes, from sample collection to processing, reporting, and laboratory revenue cycle management (lab billing).
Sample Tracking
A medical lab’s sample tracking data typically includes:
- Date of sample collection
- Test location
- Sample type and tests required
- Patient data
- Additional data customized to the lab’s workflow
Sample tracking data is captured at the time of collection and continuously updated throughout the processing cycle. As samples move between departments, the medical laboratory information system (LIS) monitors each transfer, securely documenting every step to prevent loss or delays.
Interfacing with an Interface Engine
In some cases, a laboratory information system can also function as a lab interface system by connecting with instruments, middleware, and third-party services, such as lab billing platforms, through integrated hardware and software solutions that enable seamless data exchange. The best LIS systems stand out in this area thanks to built-in interface engines that ensure accurate, reliable, and efficient data flow management.
In addition to the HL7 format, an interface engine should also be able to transfer data through FHIR, XML, X12, CSV, PDF, Flat File, ASTM, and RESTful API.
Integrated Laboratory Revenue Cycle Management
While legacy LIS systems have traditionally dealt with sample reporting only, the laboratory revenue cycle management (lab RCM) process no longer needs to be handled separately.
Advanced laboratory information system functions now include lab billing, saving time, resources, and money by automating several steps of the in-house laboratory billing process.
Thanks to its rule-based platform and full integration between the LIS system and lab RCM modules, LigoLab is a leader in all-in-one laboratory billing solutions. Customers consistently report 25-35 percent gains in net collections soon after achieving this level of interoperability.
How LIS Systems and Lab LIMS Software Help Optimize Lab Workflow
Clinical labs and pathology groups operate with diverse workflows, from sample tracking management to regulatory standard compliance, and everything in between. Although the primary lab workflow centers around sample tracking and data management, a comprehensive LIS system/lab LIMS solution can integrate future evolutions of a lab’s requirements, like digital pathology.
A clinical laboratory workflow management software package, like the LigoLab offering, integrates the various steps involved in digital pathology and sample management. It digitizes them into a repeatable, optimized process used for clinical workflow.
Placement of Test Order
The clinic or doctor orders a test, and this requisition includes both patient and sample data.
Sample Registration
Once the lab has collected the patient’s sample, the LIS system or lab LIMS generates a barcode to record sample tracking data.
Sample Processing
The LIS system/lab LIMS tracks the sample and monitors the equipment used to process it. An online computer lab management system (like the LigoLab platform) tracks and maintains a record of the time taken to run a test, the personnel handling the sample, and the laboratory instruments used for sample processing. This data is used to generate a report auditing the performance of the workflow, the equipment, and the LIS lab personnel.
Sample Report
In compliance with the lab’s data entry standards, the LIS system/lab LIMS generates a report and marks it for distribution based on client preferences.
Sample Storage
Samples are assigned to storage locations, such as shelves in a freezer, based on their barcoding. The LIS lab personnel may retrieve samples for further processing based on the stored location information.
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Why Choosing the Best Laboratory Information System Software is Key for Efficient Data Management
After the practical work, the medical LIS/lab LIMS must efficiently manage and organize the resulting data. These laboratory software systems convert raw sample data into standardized, structured entries that support seamless data exchange and system integration. For example, modern systems can interface directly with hospital electronic health record (EHR) systems, thanks to a robust interface engine and the support of a skilled interface team.
When looking for a LIS laboratory information system/LIMs lab management software, ensure you choose a future-ready platform like the LigoLab example presented here, one that seamlessly integrates multiple aspects of sample and data management and one that creates end-to-end efficiencies through rules, automation, and interoperability that empowers laboratories to run a better business and serve patients better.
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