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LIS System and Lab Billing Data are Interdependent So Why not Integrate Both into ONE Powerful Informatics Platform?
October 28, 2025
Laboratory billing (lab revenue cycle management) can be a constant source of frustration. Disconnected laboratory software systems create data silos, synchronization errors, and manual workflows that slow everything down. Missing or inaccurate data only makes matters worse, causing delayed reimbursements, denials, and unpredictable cash flow. At the same time, labs face shrinking reimbursements, rising expenses, and increasingly complex payer and regulatory requirements. Taken together, it’s clear that traditional laboratory billing solutions can no longer keep up.
Discover More: How Much is Your Outdated Laboratory Revenue Cycle Management Costing Your Lab?
It’s no longer business as usual for clinical laboratories and pathology groups, and the sooner lab leaders acknowledge this, the better.
Today’s laboratory revenue cycle management (lab RCM) landscape is increasingly difficult to navigate, and the challenges are only growing. Relying on the traditional model, where the laboratory billing process starts only after a case is finalized and reported, is no longer viable. This outdated approach to the RCM cycle puts the long-term financial stability of laboratories at risk.
The good news is that a smarter, more proactive approach is emerging. By using modern laboratory information system (LIS) technology, labs can initiate the laboratory billing process at the point of order creation, not after the fact. This shift eliminates downstream chaos and sets the stage for stronger, more predictable financial performance.
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Even better, these modern LIS systems with high-end lab RCM functionality support key features like demographic review, eligibility, and scrubbing components that greatly increase a lab’s clean claims ratio, effectively address compliance liability, and stop revenue leakage in its tracks.
Discover More: Reduce Denials and Stop Revenue Leakage With Integrated Laboratory Billing Management
Integrated LIS Systems Maximize Clinical Laboratory Workflow and Net Collections
The LigoLab platform is simultaneously an advanced laboratory information system (diagnostic lab software) built on rules and automation and an innovative laboratory billing system that improves all lab RCM processes and maximizes net collections for services rendered. It’s a one-stop informatics solution for medical labs, no matter their testing discipline, volume, or complexity.
Lab Billing Software for Labs No Longer Needs to Be Separated From Laboratory Information System Functions
The secret to LigoLab's success is its fully integrated pathology lab management system featuring a flexible LIS system software architecture and a comprehensive database that provides “one source of truth” for all laboratory workflow management, including the laboratory billing process.
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This arrangement is a game-changer for clinical labs and pathology practices interested in replacing manual labor with modern automation, achieving end-to-end data integrity, and most importantly, accelerating cash flow and increasing margin and profit.
LigoLab’s Automated, Integrated, and Transparent Laboratory Billing Solutions
LigoLab’s lab revenue cycle management module provides full transparency and control of the lab billing workflow at every stage, with up-front RCM tools like address and patient demographic data validation and insurance eligibility & discovery checks, all available in real-time and only a click away. The module also features robust workflow queues, extensive audit trail functionality, rules and automation, and flexible statement distribution.
The Billing Encounter makes this all possible by consolidating relevant information within a single data entity. This includes order and specimen information, patient and payer demographics, coding, billing, and remittance processing data. The Billing Encounter is the driving force behind the logic that supports the entire LIS system & lab RCM lifecycle.
From the Billing Encounter, data seamlessly flows into workflow queues that provide users with easy navigation and user-defined filters and templates that enable the strategic distribution of lab work with full audit trail visibility.
The lab billing module, supported by a customizable Distribution Engine, presents multiple channels for a billing department to deliver its statements, either by electronic health record (EHR), remote server, email, SMS, fax, or mail. It also features a Payment Resolution module for transaction processing, payment workflow, payment search, and payment history. Additionally, the module includes an automated and hybrid Payment Reconciliation tool.
LigoLab’s integrated medical LIS and laboratory billing system includes advanced statistical reporting tools that give users full visibility into their financial performance. With customizable dashboards, widgets, and dynamic reports, laboratories can easily track trends, key performance indicators, and benchmarks in real time. All data can be quickly extracted from the lab billing system for deeper analysis and operational insight.
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LigoLab’s comprehensive laboratory billing solutions software also features a powerful Reporting Template Engine, streamlined appeal and denial management, remittance resolution, batch claim submission, and a flexible Pricing Policies Engine. This includes support for patient and client billing policies such as payment plans, automated multi-channel statement distribution, and full compliance management.
Discover More: Best Pathology Lab Reporting Software - Buyers Guide and Checklist
Move Your Laboratory RCM Cycle Upstream with LigoLab’s Laboratory Billing Solutions
Let’s face it. The laboratory billing process includes a complex mixture of documentation, coding, compliance, and regulation between multiple parties. One incomplete form, coding error, or missed deadline can easily result in a denial.
Years ago, when margins were higher and medical labs were more profitable, enhanced laboratory revenue cycle management wasn’t the priority item it is today. Most labs at that time relied on standalone and siloed laboratory billing software, even though this often resulted in high denials and significant write-offs. Much of this was caused by starting the RCM cycle only after the lab report had been submitted to the client.
Fast forward to the present, and that same laboratory billing process simply doesn’t work any longer. It’s no longer sustainable.
Fortunately, a new perspective coupled with new RCM process technology are taking over, with medical lab owners now able to take full control of the situation and move forward with new and advanced laboratory billing solutions that protect their businesses from external threats.
One such lab is Avero Diagnostics.
Laboratory Revenue Cycle Management Case Study
With LigoLab, medical labs across all genres can now unite their operations and finances within an all-in-one laboratory information system software that features a fully embedded lab billing module. LigoLab’s lab RCM leverages automation, integration, and transparency to mitigate denials and transform clinical lab workflow and profitability.
To learn more, we invite you to take a few moments to read a case study featuring Avero Diagnostics.
In this case study, we dive deep into the issues that Avero was having with its standalone laboratory billing system, and we examine the positive results after the full-service high-volume laboratory decided to drop its prior underperforming lab RCM solution and move to LigoLab’s fully integrated LIS system & lab RCM informatics platform.
LigoLab Case Study: Documenting the Avero Diagnostics Move From a Legacy Lab RCM System to LigoLab’s All-in-One Lab Informatics Platform
LigoLab’s All-in-One LIS System and Laboratory Billing Platform
For two decades, LigoLab has been a trusted LIS company for clinical laboratories and pathology groups, supporting hundreds of facilities with the latest pathology lab software technology and innovative lab informatics solutions.
Discover More: Navigating the Future of Pathology - The LigoLab Advantage
Transform your lab’s future today.
Request a demo to see why hundreds of laboratories trust LigoLab’s all-in-one medical LIS and lab billing platform to power their success.
